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Abrupt Outpatient Withdrawal of Medication in Analgesic-Abusing Migraineurs
Lancet 337:1442-1443, Hering,T.&Steiner,T.J., 1991
See this aricle in Pubmed

Article Abstract
46 migraineurs with secondary chronic daily headache were treated for medication abuse as outpatients by abrupt withdrawal of the offending drugs.The patients were supported with adequate explanation of the disorder,regular follow-up,amitriptyline(10 mg at night),and naproxen(500 mg)for relief of headache symptoms.By 6 months of follow-up 37 patients had relief from chronic headaches,and analgesic intake had become intermittent and appropriate to the original occasional migraine episodes. 6 had substantially reduced analgesic intake,but headache severity was unchanged;2 had not managed to reduce intake and headache was unchanged; and 1 patient withdrew after the first visit.
 
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drug abuse
drug addiction
drug induced neurologic disorders
drug withdrawal
ergotamine
headache
headache,drug induced
headache,rebound
headache,treatment of
migraine
migraine,treatment of
treatment of neurologic disorder

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